Acute chest syndrome in pregnant women with hemoglobin SC disease

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Acute Chest Syndrome in Pregnant Women with Hemoglobin SC Disease

Acute chest syndrome (ACS) is a severe pulmonary complication in pregnant women with sickle cell disease (SCD). Between January 1998 and December 2002, ACS occurred in 4 of 286 pregnant women with SCD in Bahrain (1.2%), and it was associated with two maternal deaths. In the United States, 10 pregnant women (0.06%) were diagnosed with ACS out of 17,952 deliveries in women with SCD from 2000 to 2...

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Dyspnea with hemoglobin SC disease.

BUMC PROCEEDINGS 2002;15:86–90 CASE PRESENTATION LINDA S. BANG, MD: A 41-year-old African American woman with sickle cell disease presented to the Baylor University Medical Center emergency department with dyspnea and dry cough for 3 weeks and back, leg, and chest pain for 2 to 3 days. The hemoglobin SC disease had been first diagnosed during pregnancy. Pleural tuberculosis with a left-sided ef...

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Acute chest syndrome in sickle-cell disease.

25 consecutive episodes of acute chest syndrome in 13 adult patients with sickle-cell disease were studied retrospectively. Chest symptoms were present on admission in 23 of 25 episodes. Abnormal chest signs and an abnormal chest X-ray were present on admission in only 11 and 9 episodes, respectively, but developed later in the remainder. The 9 episodes with bilateral radiological changes were ...

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Elevated hypercoagulability markers in hemoglobin SC disease.

Hemoglobin SC disease is a very prevalent hemoglobinopathy; however, very little is known about this condition specifically. There appears to be an increased risk of thromboembolic events in hemoglobin SC disease, but studies evaluating the hemostatic alterations are lacking. We describe the findings of a cross-sectional observational study evaluating coagulation activation markers in adult pat...

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Acute chest syndrome in adults with sickle cell disease.

STUDY OBJECTIVES Acute chest syndrome (ACS) is a frequent and potentially severe pulmonary illness in sickle cell disease (SCD). The aim of the study was to report the clinical features and outcome of consecutive ACS episodes in adult patients in a French SCD center. All patients were treated according to an uniform therapeutic protocol applying transfusion only in the more severe clinical form...

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ژورنال

عنوان ژورنال: Clinics

سال: 2009

ISSN: 1807-5932

DOI: 10.1590/s1807-59322009000900015